Substrate: PLC gamma 2 (Involved in transmembrane signaling)
Seq-ID: P16885 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-60791   Z512B_HUMAN
MINT-74685   EGFR_HUMAN
MINT-74686   ERBB2_HUMAN
MINT-7252126   P85A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide phospholipase C activity,
signal transducer activity,
protein binding		 plasma membrane phospholipid catabolic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 733 HSLYRKMRLRYPVTPELLERY - 18083107
HTP
1.00
 - -
0.22
 - medium
Y 743 YPVTPELLERYNMERDINSLY Fyn 12181444
LTP
0.05
 - -
0.27
 - medium
Y 743 YPVTPELLERYNMERDINSLY Lck 12181444
LTP
0.05
 - -
0.27
 - medium
Y 743 YPVTPELLERYNMERDINSLY Lyn 12181444
LTP
0.05
 - -
0.27
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS - 11507089
LTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS Lck 11606584
LTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS SRC 11606584
LTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS BTK 11606584
LTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS Lck 12181444
LTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 753 YNMERDINSLYDVSRMYVDPS - 15144186
HTP
0.37
 PLCG2 SH2 -
0.26
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM - 11507089
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM Lck 11606584
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM SRC 11606584
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM BTK 11606584
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM Lck 12181444
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM BTK 14656219
LTP
0.98
 PLCG2 SH2 -
0.33
 - medium
Y 1197 RPVLESEEELYSSCRQLRRRQ BTK 11507089
LTP
1.00
 - -
0.33
 - medium
Y 1197 RPVLESEEELYSSCRQLRRRQ Lck 15184383
LTP
1.00
 - -
0.33
 - medium
Y 1217 QEELNNQLFLYDTHQNLRNAN BTK 11507089
LTP
1.00
 - -
0.35
 - medium
Y 1217 QEELNNQLFLYDTHQNLRNAN Lck 15184383
LTP
1.00
 - -
0.35
 - medium
Y 1217 QEELNNQLFLYDTHQNLRNAN BTK 17239630
LTP
1.00
 - -
0.35
 - medium
Y 1245 FSVNENQLQLYQEKCNKRLRE - 11971963
LTP
0.00
 - -
0.32
 - medium
Y 1245 FSVNENQLQLYQEKCNKRLRE - 15144186
HTP
0.00
 - -
0.32
 - medium

Substrate: PLC gamma 2 (Involved in transmembrane signaling)
Seq-ID: P24135 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide phospholipase C activity,
signal transducer activity,
protein binding		 membrane fraction response to magnesium ion,
response to ATP,
phospholipid catabolic process,
elevation of cytosolic calcium ion concentration
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 753 YNMERDINSLYDVSRMYVDPS BTK 11507089
LTP
0.37
 - -
0.26
 - low
Y 753 YNMERDINSLYDVSRMYVDPS BTK 11606584
LTP
0.37
 - -
0.26
 - low
Y 753 YNMERDINSLYDVSRMYVDPS - 12181444
LTP
0.37
 - -
0.26
 - low
Y 759 INSLYDVSRMYVDPSEINPSM BTK 11507089
LTP
0.98
 - -
0.34
 - low
Y 759 INSLYDVSRMYVDPSEINPSM BTK 11606584
LTP
0.98
 - -
0.34
 - low
Y 759 INSLYDVSRMYVDPSEINPSM - 12181444
LTP
0.98
 - -
0.34
 - low
Y 1197 RPVLESEEELYSSCRQLRRRQ BTK 11507089
LTP
1.00
 - -
0.33
 - low
Y 1217 QEELNNQLFLYDTHQNLRGAN BTK 11507089
LTP
1.00
 - -
0.33
 - low

Substrate: PLC gamma 2 (Involved in transmembrane signaling)
Seq-ID: ENSMUSP00000079991 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19484   REPS1_MOUSE
MINT-19500   SH3K1_MOUSE
MINT-19548   CRYAB_MOUSE
MINT-19577   CAP1_MOUSE
MINT-19612   ERRFI_HUMAN
MINT-19667   SPTB2_MOUSE
MINT-19706   TOX4_MOUSE
MINT-19733   SPY2_MOUSE
MINT-19846   SHIP1_MOUSE
MINT-59438   EPOR_MOUSE
MINT-7214337   LYN_MOUSE
MINT-7214415   BLK_MOUSE
MINT-7214472   FYN_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide phospholipase C activity,
signal transducer activity,
protein binding		 regulation of gene expression,
follicular B cell differentiation,
negative regulation of programmed cell death,
phospholipid catabolic process,
T cell receptor signaling pathway,
activation of store-operated calcium channel activity,
inositol trisphosphate biosynthetic process,
response to lipopolysaccharide
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 753 YNMERDINSLYDVSRMYVDPS - 15509800
LTP
0.37
 - -
0.26
 - medium
Y 759 INSLYDVSRMYVDPSEINPSM - 15509800
LTP
0.98
 - -
0.34
 - medium
Y 1217 QEELNNQLFLYDTHQNLRGAN - 15509800
LTP
1.00
 - -
0.33
 - medium

Valid HTML 4.01 Transitional